Vegetarian Collagen

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This scientific research is for informational use only. The results reported may not necessarily occur in all individuals. Care/of provides this information as a service. This information should not be read to recommend or endorse any specific products.

Eggshell membrane is naturally high in collagen, elastin, and keratin, three of the most important proteins for healthy hair, skin, and nails, as well as hyaluronic acid. In several studies, participants who were given eggshell membrane over several months saw a significant improvement in skin elasticity and firmness, and reported shinier, healthier hair.

Hair and nail health

While the benefits for oral consumption of eggshell membrane on skin health parameters have been established (above) through well conducted clinical trials, positive effects on hair and nail health are still emerging. A pilot study was conducted to investigate the hypothesis that eggshell membrane can also support the health of human hair and nails. A pilot study was conducted to assess 300 mg eggshell membrane orally ingested on hair and nail health after 50 days. Using a self-assessment questionnaire, 67% of volunteers reported that they were satisfied with overall hair health and condition. 56% selfreported improved hair brightness and hydration and approximately 45% self-reported improvements in hair thickness and loss. Additionally, 28% saw improvement in hair volume after 50 days. With respect to nail health, volunteers reported improved nail hardness, growth and nail irregularity of 61%, 50% and 28%, respectively. Furthermore, 50% of volunteers reported that they were satisfied with overall nail condition (1).

References
  1. Beneficial Effects of Oral Supplementation with Ovoderm on Human Skin Physiology: Two Pilot Studies
    Aguirre A, Gil-Quintana E, Fenaux M, Erdozain S et al,
    J. Diet Suppl.,
    2017

Skin health

In a randomized, double-blind, placebo-controlled study, healthy participants with altered skin barrier function were given an oral dietary supplement of 300mg eggshell membrane for 60 days and results from the trial showed significant improvement in the skin’s barrier function and trans epidermal water loss (TEWL). TEWL is a clinical tool that is used to measure the skin barrier function, which is the normal permeation of water through the skin into the atmosphere. In the eggshell membrane group, TEWL was significantly reduced by 43.2% after 60 days of treatment, while there was no significant change in the placebo group. Additionally, significant improvement in skin’s elasticity, firmness and fatigue were also found after 60 days. Skin elasticity was improved by 13.3%, firmness was significantly improved by 65.8%, and skin fatigue was decreased by 35.6%. Skin fatigue was represented by tiring effects of the skin after repeated suction and release of the skin and measuring capability of returning to its original position following deformation (1).

Another randomized, placebo-controlled clinical study giving volunteers 300mg eggshell membrane for 60 days found a decline in water loss of the skin of about 19%, where the placebo group only had a decrease of about 1%. Skin firmness and fatigue were positively affected with significant improvements of 51% and 33%, respectively, after 60 days. Elasticity parameters were also measured and subjects taking eggshell membrane showed a significant benefit of 25%, while no significant changes were assessed in the placebo group. Finally, eye contour appearance was assessed in 3 volunteers and showed visual difference of the skin from the eye contour after 60 days of oral ingestion of eggshell membrane. Overall, oral ingestion of an eggshell membrane supplement demonstrated significant improved on skin physiology (2).

In addition to the clinical trials outlined above, researchers conducted 2 pilot studies to assess ingestion of eggshell membrane on various skin health parameters. All (100%) of volunteers from the first pilot study observed improvement on their general facial skin condition and softness. 94% of participants reported general improvement in their body skin condition. With respect to hydration, 94% and 89% selfreported improvement in facial and body skin hydration, respectively. Finally, significant improvements in skin brightness (83%) and smoothness (72%) were also reported.

In pilot study 2, three skin parameters were assessed: skin hydration, pigmentation and elasticity. After 5 weeks of ingestion of 300 mg eggshell membrane, volunteers revealed statistically significant improvement in skin elasticity compared to baseline. While the other two parameters did not show significant changes, a tendency on reduced skin pigmentation was observed (3).

References
  1. Ovoderm an effective treatment to improve skin condition in patients with altered skin barrier function
    Aguirre A, Gil-Quintana E, La Nuex M,
    J Skin,
    2018
  2. Supplementation with Ovoderm Reduces the Clinical Signs of Skin Aging. A Double-Blind, Placebo-Controlled Study
    Gil-Quintana E, La Nuez M, Aguirre A,
    Clin. Res. Dermatol.,
    2018
  3. Beneficial Effects of Oral Supplementation with Ovoderm on Human Skin Physiology: Two Pilot Studies
    Aguirre A, Gil-Quintana E, Fenaux M, Erdozain S et al,
    J. Diet Suppl.,
    2017
The following scientific research is for informational use only. Care/of provides this information as a service and does not receive compensation for studies referenced. This information should not be read to recommend or endorse any specific products. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease.
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